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Rabbit Anti-Rad52  antibody (bs-1878R)  
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說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
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大包裝/詢價
產(chǎn)品編號 bs-1878R
英文名稱 Rabbit Anti-Rad52  antibody
中文名稱 Rad52抗體
別    名 DNA repair protein RAD52; DNA repair protein RAD52 homolog; RAD 52; RAD52 homolog (S. cerevisiae); RAD52 homolog; Recombination protein RAD52; Rhabdomyosarcoma antigen MU RMS 40.23; DNA repair protein RAD52 homolog; RAD52_HUMAN; RAD52 homolog.  
研究領域 染色質和核信號  轉錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 46kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Rad52: 101-200/418 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. [provided by RefSeq, Jul 2008]

Function:
Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.

Subunit:
The full-length protein forms heptameric rings. Interacts with ABL1.

Subcellular Location:
Nucleus (Potential).

Post-translational modifications:
Phosphorylated upon DNA damage by ABL1, and probably by ATM or ATR.

Similarity:
Belongs to the RAD52 family.

SWISS:
P43351

Gene ID:
5893

Database links:

Entrez Gene: 5893 Human

Omim: 600392 Human

SwissProt: P43351 Human

Unigene: 410355 Human



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