| 產(chǎn)品編號 | bs-2463R |
| 英文名稱 | Rabbit Anti-TNFSF4 antibody |
| 中文名稱 | 腫瘤壞死因子配體超家族成員4抗體 |
| 別 名 | CD 134L; CD 252; CD134; CD134 ligand; CD134L; CD252; CD252 antigen; glycoprotein 34 kd; Glycoprotein Gp34; GP34; OX-40L; OX40 antigen ligand; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; TNFL4_RAT; Tnfsf4; Tumor necrosis factor (ligand) superfamily member 4; Tumor necrosis factor ligand superfamily member 4; TXGP1. |
| 研究領(lǐng)域 | 細胞生物 免疫學(xué) 細胞表面分子 淋巴細胞 t-淋巴細胞 細胞因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat (predicted: Mouse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 22kDa |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from rat TNFSF4: 141-199/199 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq] Function: Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. Subunit: Homotrimer (Probable). Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Detected in T-cell lines, but not in a macrophage cell line. Similarity: Belongs to the tumor necrosis factor family. SWISS: Q9Z2P3 Gene ID: 89814 Database links: Entrez Gene: 7292 Human Entrez Gene: 22164 Mouse Omim: 603594 Human SwissProt: P23510 Human SwissProt: P43488 Mouse Unigene: 181097 Human Unigene: 4994 Mouse Unigene: 30043 Rat |
| 產(chǎn)品圖片 |
Sample:
Thymus(Rat) Lysate at 40 ug
Primary: Anti- TNFSF4 (bs-2463R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 22 kD
Observed band size: 33 kD
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