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Rabbit Anti-CXCL3  antibody (bs-2547R)  
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產(chǎn)品編號 bs-2547R
英文名稱 Rabbit Anti-CXCL3  antibody
中文名稱 生長調(diào)節(jié)致癌基因gamma/GROγ抗體
別    名 CXCL3_HUMAN; C-X-C motif chemokine 3; GRO-gamma(1-73); Growth-regulated protein gamma (GRO-gamma); Macrophage inflammatory protein 2-beta (MIP2-beta); GRO-gamma(5-73); GRO3; GROG; SCYB3; MIP2B; MIP-2b; CINC-2b;  GROγ; GRO-γ; GRO γ.
Specific References  (4)     |     bs-2547R has been referenced in 4 publications.
[IF=6.166] Sugandha Saxena. et al. Differential expression profile of CXC-receptor-2 ligands as potential biomarkers in pancreatic ductal adenocarcinoma. Am J Cancer Res. 2022; 12(1): 68–90  IHC ;  Mouse,Human.  
[IF=3.762] Wu L et al. Interleukin17–CXCR2 axis facilitates breast cancer progression by up-regulating neutrophil recruitment. Am J Pathol. 2019 Oct 22. pii: S0002-9440(19)30768-0.  IHC-P ;  Mouse.  
[IF=3.53] Gui S, Ni S, Jia J, Gong Y, Gao L, et al. (2014) Inconformity of CXCL3 Plasma Level and Placenta Expression in Preeclampsia and Its Effect on Trophoblast Viability and Invasion. PLoS ONE 9(12): e114408.  IHC-P ;  Human.  
[IF=2.766] Gui et al. Inconformity of CXCL3 plasma level and placenta expression in preeclampsia and its effect on trophoblast viability and invasion. (2014) PLoS.One. 9:e114408  IHC ;  Human.  
研究領域 腫瘤  免疫學  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 12kDa
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CXCL3: 35-107/107 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Growth Regulated Protein gamma (GRO gamma) is a cytokine that may play a role in inflammation and affects endothelial cells in an autocrine fashion. It belongs to the intercrine alpha family (small cytokine c-x-c) (chemokine cxc).

Function:
Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.

Subcellular Location:
Secreted.

Post-translational modifications:
N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.

Similarity:
Belongs to the intercrine alpha (chemokine CxC) family.

SWISS:
P19876

Gene ID:
2921

Database links:

Entrez Gene: 2921 Human

Omim: 139111 Human

SwissProt: P19876 Human

Unigene: 89690 Human



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