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Rabbit Anti-Ly-6G  antibody (bs-2576R)  
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產(chǎn)品編號 bs-2576R
英文名稱 Rabbit Anti-Ly-6G  antibody
中文名稱 淋巴細胞抗原6G抗體
別    名 Gr-1; Gr1; Ly 6G; Ly-6G.1; Ly6G; lymphocyte antigen 6 complex locus G; Lymphocyte antigen 6G.  
Specific References  (7)     |     bs-2576R has been referenced in 7 publications.
[IF=16.264] Schukur, Lina, et al. "Implantable synthetic cytokine converter cells with AND-gate logic treat experimental psoriasis." Science Translational Medicine7.318 (2015): 318ra201-318ra201.  IHC-P ;  Mouse.  
[IF=6.17] Ying Xu. et al. PINK1-mediated mitophagy protects against hepatic ischemia/reperfusion injury by restraining NLRP3 inflammasome activation. Free Radical Bio Med. 2020 Nov;160:871  IF,IHC ;  Mouse.  
[IF=4.12] Arecco et al. Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation. (2016) Sci.Rep. 6:24708  IF ;  Mouse.  
[IF=2.319] Xinhong WANG. et al. Anti-inflammatory effect of HGF responses to oral traumatic ulcers using an HGF-Tg mouse model. 2021 Nov 25  IHC ;  Mouse.  
[IF=0] Stephanie Arnold. et al. Single and Multiplex Immunohistochemistry to Detect Platelets and Neutrophils in Rat and Porcine Tissues. Methods and Protocols. 2022 Oct;5(5):71  IHC ;  Rat, Pig.  
[IF=0] Wanga X et al. Anti-inflammatory effect of HGF responses to traumatic oral ulcers using an HGF-Tg mouse model. Research Square; 2020 Jan 22.  IHC-P ;  Mouse.  
[IF=0] Tsunashima et al. Accumulated myeloid-derived suppressor cells demonstrate distinct phenotypes and functions in two non-alcoholic steatohepatitis mouse models. (2015) Hepatobiliary.Surg.Nutr. 4:313-319  FC/FACS,IHC ;  Mouse.  
研究領(lǐng)域 細胞生物  免疫學(xué)  干細胞  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 14kDa
檢測分子量 21-25
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Ly-6G/Gr-1: 51-134/134 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Ly6G is a GPI-anchored protein, that is also known as the myeloid differentiation antigen Gr1. The antigen is transiently expressed on monocytes in the bone marrow. The level of antigen expression in the bone marrow directly correlates with granulocyte differentiation and maturation. Ly6G is expressed predominantly on neutrophils, also in a subset of eosinophils, differentiating pre-monocytes, and plasmacytoid dendritic cells.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor (By similarity).

Tissue Specificity:
Expressed in bone marrow.

Similarity:
Contains 1 UPAR/Ly6 domain.

SWISS:
P35461

Gene ID:
546644

Database links:

Entrez Gene: 546644 Mouse

SwissProt: P35461 Mouse



Ly6G屬于是Ly-6家族成員,主要表達于T細胞、單核細胞,中性白細胞等,在抑制抗腫瘤和T細胞的應(yīng)答方面起著重要作用。主要定位于細胞膜、細胞漿。
產(chǎn)品圖片
Lane 1: Recombinant mouse Ly-6G protein (His-tag) Primary: Anti-Ly-6G (bs-2576R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 14 kDa Observed band size: 18 kDas
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