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Rabbit Anti-SIGLEC6  antibody (bs-2704R)  
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產品編號 bs-2704R
英文名稱 Rabbit Anti-SIGLEC6  antibody
中文名稱 SIGLEC6/CD33L抗體
別    名 Sialic acid-binding Ig-like lectin 6; CD33L; CD33L1; OBBP1; CDw327; CD327; OBBP1; Full=Sialic acid-binding Ig-like lectin 6; Siglec-6; CD33 antigen-like 1; CDw327 Obesity-binding protein 1; OB-BP1; SIGL6_HUMAN.  
研究領域 免疫學  細胞表面分子  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 47kDa
細胞定位 細胞膜 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SIGLEC6: 101-200/453 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Function:
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Subunit:
Interacts with LEP.

Subcellular Location:
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.

Tissue Specificity:
Expressed at high levels in placenta (cyto-and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine.

Similarity:
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
O43699

Gene ID:
946

Database links:

Entrez Gene: 946 Human

Omim: 604405 Human

SwissProt: O43699 Human

Unigene: 720304 Human



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