| 產(chǎn)品編號(hào) | bs-3644R |
| 英文名稱 | Rabbit Anti-KLF9 antibody |
| 中文名稱 | 轉(zhuǎn)錄因子KLF9抗體 |
| 別 名 | Basic transcription element binding protein 1; BTE binding protein 1; BTEB 1; BTEB; BTEB1; GC box binding protein 1; KLF 9; Krueppel like factor 9; Transcription factor BTEB 1; Transcription factor BTEB1. |
 |
Specific References (1) | bs-3644R has been referenced in 1 publications.
[IF=2.145] Yong Luo. et al. Identification of a Necroptosis-Related Prognostic Index and Associated Regulatory Axis in Kidney Renal Clear Cell Carcinoma. INT J GEN MED. 2022; 15: 5407–5423 IHC ; Human.
|
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 細(xì)胞分化 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 27kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KLF9: 151-244/244 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
KLF9 is a transcription factor that binds to GC box promoter elements. It activates mRNA synthesis selectively from genes containing tandem repeats of GC boxes but represses genes with a single GC box. KLF9 belongs to the Sp1 C2H2 type zinc finger protein family. SWISS: Q13886 Gene ID: 687 Database links: Entrez Gene: 687 Human Entrez Gene: 16601 Mouse Omim: 602902 Human SwissProt: Q13886 Human SwissProt: O35739 Mouse Unigene: 150557 Human Unigene: 602267 Human Unigene: 291595 Mouse Unigene: 392684 Mouse Unigene: 19481 Rat KLF9(BTEB)屬于Krueppel樣轉(zhuǎn)錄因子家族成員之一, 是參與真核細(xì)胞基因轉(zhuǎn)錄調(diào)控的鋅指蛋白, 主要通過(guò)羧基末端鋅指與靶基因啟動(dòng)子區(qū)的GC或GT/CACC box結(jié)合調(diào)節(jié)靶基因的轉(zhuǎn)錄。KLF9與其他轉(zhuǎn)錄因子、和輔助激活抑制因子相互作用完成對(duì)基因轉(zhuǎn)錄的調(diào)控, 在生殖發(fā)育、細(xì)胞增殖分化、細(xì)胞周期調(diào)控等方面發(fā)揮作用。 |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Human K562 cell lysates
Lane 2: Human U251 cell lysates
Lane 3: Human 293T cell lysates
Primary: Anti-KLF9 (bs-3644R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kDa
Observed band size: 27 kDa
|
