| 產(chǎn)品編號(hào) | bs-3852R |
| 英文名稱 | Rabbit Anti-TNFRSF19 antibody |
| 中文名稱 | 腫瘤壞死因子配體超家族成員19抗體 |
| 別 名 | TROY; TAJ alpha; TAJ; TNFRSF 19; TNFRSF19; Tnfrsf20; Toxicity and JNK inducer; TRADE; Tumor necrosis factor receptor superfamily member 19. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 生長因子和激素 轉(zhuǎn)錄調(diào)節(jié)因子 細(xì)胞表面分子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,GuineaPig (predicted: Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 43kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TROY: 102-200/423 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
TROY is a member of the TNF receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate the JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. Subunit: Associates with TRAF1, TRAF2, TRAF3 and TRAF5. Interacts with LINGO1. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes. Similarity: Contains 3 TNFR-Cys repeats. SWISS: Q9NS68 Gene ID: 55504 Database links: Entrez Gene: 55504 Human Entrez Gene: 29820 Mouse Omim: 606122 Human SwissProt: Q9NS68 Human SwissProt: Q9JLL3 Mouse Unigene: 149168 Human Unigene: 730848 Human Unigene: 281356 Mouse |
| 產(chǎn)品圖片 |
Sample:
Siha(Human) Cell Lysate at 30 ug
Primary: Anti- TNFRSF19 (bs-3852R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 43 kD
Observed band size: 43 kD
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