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Rabbit Anti-ADCY9  antibody (bs-3926R)  
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產(chǎn)品編號 bs-3926R
英文名稱 Rabbit Anti-ADCY9  antibody
中文名稱 腺苷酸環(huán)化酶9抗體
別    名 ADCY 9; Adenylate cyclase 9; Adenylate cyclase type 9; Adenylate cyclase type IX; Adenylyl cyclase 9; ATP pyrophosphate lyase 9; KIAA0520; Type IX adenylyl cyclase; Type IX ATP pyrophosphate lyase; ADCY9_HUMAN.  
Specific References  (1)     |     bs-3926R has been referenced in 1 publications.
[IF=3.329] Enivwenaye E.W. Nabofa et al. Cardiovascular Effects of Caffeine in Rabbits Involve Beta-2 Adrenergic Receptor Activation.  IHC ;  rabbit.  
研究領(lǐng)域 腫瘤  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  生長因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human,Rabbit,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 150kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ADCY9: 251-350/1353 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008].

Function:
May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in multiple cells of the lung, with expression highest in airway smooth muscle.

Similarity:
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 2 guanylate cyclase domains.

SWISS:
O60503

Gene ID:
115

Database links:
UniProtKB/Swiss-Prot: O60503.4

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