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Rabbit Anti-GALK1/Galactose kinase  antibody (bs-3983R)  
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產(chǎn)品編號 bs-3983R
英文名稱 Rabbit Anti-GALK1/Galactose kinase  antibody
中文名稱 半乳糖激酶1抗體
別    名 Galactokinase 1; Galactose kinase; GALK1; GALK 1; GALK; GK1; GLK; GLK1; EC 2.7.1.6; GALK1_HUMAN; Galactokinase; Galactose kinase.0.  
研究領域 腫瘤  細胞生物  免疫學  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 42kDa
細胞定位 細胞漿 細胞外基質(zhì) 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Galactose kinase: 151-250/392 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts in the adult population. GALK1 sequence shares the greatest level of conservation, 44.5% identity with that from E. coli and 34.6% amino acid identity with the product of the human GALK2 gene.

Function:
Major enzyme for galactose metabolism.

Subunit:
Homodimer (Probable).

DISEASE:
Defects in GALK1 are the cause of galactosemia II (GALCT2) [MIM:230200]. Galactosemia II is an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses.

Similarity:
Belongs to the GHMP kinase family. GalK subfamily.

SWISS:
P51570

Gene ID:
2584

Database links:
UniProtKB/Swiss-Prot: P51570.1

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