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Rabbit Anti-Growth Arrest Specific Protein 7  antibody (bs-4279R)  
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產(chǎn)品編號(hào) bs-4279R
英文名稱 Rabbit Anti-Growth Arrest Specific Protein 7  antibody
中文名稱 生長(zhǎng)休止特定蛋白7抗體
別    名 GAS 7; GAS-7; Gas7; GAS7_HUMAN; Growth arrest specific 7; Growth arrest-specific protein 7; KIAA0394; MGC1348; MLL/GAS7; MLL/GAS7 fusion protein.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 54kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GAS7/Growth Arrest Specific Protein 7: 361-476/476 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Growth arrest specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. It may play a role in neuronal development by promoting maturation and morphological differentiation of cerebellar neurons. Several transcript variants encoding proteins which vary in the N terminus have been described.

Function:
May play a role in promoting maturation and morphological differentiation of cerebellar neurons.

Subcellular Location:
Cytoplasm (By similarity).

DISEASE:
Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX.

Similarity:
Contains 1 FCH domain.
Contains 1 SH3 domain.
Contains 1 WW domain.

SWISS:
O60861

Gene ID:
8522

Database links:

Entrez Gene: 8522 Human

Omim: 603127 Human

SwissProt: O60861 Human

SwissProt: O55148 Rat

Unigene: 258855 Human

Unigene: 462214 Human

Unigene: 17160 Rat



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