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Rabbit Anti-ETV7  antibody (bs-5965R)  
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產(chǎn)品編號 bs-5965R
英文名稱 Rabbit Anti-ETV7  antibody
中文名稱 轉錄因子ETV7抗體
別    名 TELB; ETS related protein Tel2; TEL 2; Tel related Ets factor; TEL2; Transcription factor Tel 2; TREF.ETV7_HUMAN  
研究領域 腫瘤  免疫學  染色質(zhì)和核信號  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 37kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ETV7: 251-341/341 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).[provided by RefSeq, May 2011].

Function:
Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in hematopoietic tissues.

Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.
Contains 1 PNT (pointed) domain.

SWISS:
Q9Y603

Gene ID:
51513

Database links:

Entrez Gene: 51513 Human

Omim: 605255 Human

SwissProt: Q9Y603 Human

Unigene: 272398 Human



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