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Rabbit Anti-TSPY1  antibody (bs-6607R)  
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產品編號 bs-6607R
英文名稱 Rabbit Anti-TSPY1  antibody
中文名稱 睪丸特異定蛋白質編碼Y1抗體
別    名 DYS14; pJA 923; pJA923; Testis specific protein Y linked 1; Testis specific Y encoded protein 1; TSPY 1; TSPY; TSPY1_HUMAN.  
研究領域 腫瘤  細胞生物  發(fā)育生物學  染色質和核信號  干細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 34kDa
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TSPY1: 231-308/308 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The function of this protein is unknown. TSPY genes are located on the Y-chromosome of several mammalian species. TSPY encodes a testis-specific protein 1, which probably acts as nucleosome-binding transcription factor. Homology with the SET/NAP/DENTT oncogene family suggest a role in spermatogonic cell division and seminal oncogenesis.

Function:
May be involved in sperm differentiation and proliferation.

Subcellular Location:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also found in nucleus.

Tissue Specificity:
Specifically expressed in testicular tissues. Isoform 1 and isoform 2 are expressed in spermatogonia and spermatocytes. Found in early testicular carcinoma in situ, spermatogonial cells in testicular tissues of 46,X,Y female and in prostate cancer cell lines.

Post-translational modifications:
Phosphorylated.

Similarity:
Belongs to the nucleosome assembly protein (NAP) family.

SWISS:
Q01534

Gene ID:
7258

Database links:

Entrez Gene: 7258 Human

Entrez Gene: 728137 Human

Omim: 480100 Human

SwissProt: Q01534 Human

Unigene: 556121 Human



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