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Rabbit Anti-PELO  antibody (bs-7821R)  
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產(chǎn)品編號 bs-7821R
英文名稱 Rabbit Anti-PELO  antibody
中文名稱 PELO蛋白抗體
別    名 CGI17; pelo; PELO_HUMAN; pelota (Drosophila) homolog; pelota homolog; PRO1770; Protein pelota homolog.  
Specific References  (2)     |     bs-7821R has been referenced in 2 publications.
[IF=5.636] Nele Hug. et al. A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation. RNA. 2022 Sep;28(9):1224-1238  IP, WB ;  Human.  
[IF=3.231] Peifang Yang. et al. A Proteomic Study of the Effect of N-acetylcysteine on the Regulation of Early Pregnancy in Goats. ANIMALS. 2022 Jan;12(18):2439  IHC ;  Goat.  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  細(xì)胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 43kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PELO: 141-240/385 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity.

Function:
Required for normal chromosome segregation during celldivision and genomic stability (By similarity). May function inrecognizing stalled ribosomes and triggering endonucleolyticcleavage of the mRNA, a mechanism to release non-functionalribosomes and degrade damaged mRNAs. May have ribonuclease activity(Potential).

Subcellular Location:
Nucleus (Potential). Cytoplasm (Bysimilarity).

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the eukaryotic release factor 1 family.Pelota subfamily.

SWISS:
Q9BRX2

Gene ID:
53918

Database links:

Entrez Gene: 53918 Human

Omim: 605757 Human

SwissProt: Q9BRX2 Human

Unigene: 644352 Human

Unigene: 669791 Human



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