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Rabbit Anti-DCTN2  antibody (bs-7836R)  
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產(chǎn)品編號 bs-7836R
英文名稱 Rabbit Anti-DCTN2  antibody
中文名稱 動力蛋白激活蛋白2抗體
別    名 50 kD dynein associated polypeptide; 50 kDa dynein associated polypeptide; 50 kDa dynein-associated polypeptide; DCTN-50; DCTN2; DCTN2_HUMAN; DCTN50; dynactin 2 (p50); dynactin 2; dynactin complex 50 kD subunit; Dynactin complex 50 kDa subunit; Dynactin subunit 2; p50 dynamitin; RBP50.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  細(xì)胞分化  細(xì)胞骨架  細(xì)胞外基質(zhì)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 44kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Dynamitin/DCTN2: 65-150/401 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

Function:
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

Subunit:
Subunit of dynactin, a multiprotein complex associated with dynein. Interacts with BICD2 and CEP135.

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome. Membrane; Peripheral membrane protein.

Similarity:
Belongs to the dynactin subunit 2 family.

SWISS:
Q13561

Gene ID:
10540

Database links:

UniProtKB/Swiss-Prot: Q13561.4

Entrez Gene: 10540 Human

Entrez Gene: 69654 Mouse

Omim: 607376 Human

SwissProt: Q13561 Human

SwissProt: Q99KJ8 Mouse

Unigene: 289123 Human

Unigene: 167537 Mouse



產(chǎn)品圖片
Sample: Spleen (Mouse) Lysate at 40 ug Lung (Mouse) Lysate at 40 ug Primary: Anti- DCTN2 (bs-7836R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44 kD Observed band size: 44 kD
Sample: Bone (Mouse) Lysate at 40 ug Primary: Anti- DCTN2 (bs-7836R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44 kD Observed band size: 44 kD
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