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Rabbit Anti-BMP9  antibody (bs-6909R)  
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產(chǎn)品編號(hào) bs-6909R
英文名稱 Rabbit Anti-BMP9  antibody
中文名稱 骨形態(tài)發(fā)生蛋白9抗體
別    名 BMP 9; BMP-9; Bone morphogenetic protein 9; GDF 2; GDF2; GDF-2; growth differentiation factor 2; GDF2_HUMAN.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞分化  細(xì)胞外基質(zhì)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Rabbit)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BMP9: 351-429/429 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. [provided by RefSeq, Jul 2008].

Function:
Could be involved in bone formation.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted.

Similarity:
Belongs to the TGF-beta family.

SWISS:
Q9UK05

Gene ID:
2658

Database links:

Entrez Gene: 2658 Human

Entrez Gene: 12165 Mouse

Entrez Gene: 290921 Rat

Omim: 605120 Human

SwissProt: Q9UK05 Human

SwissProt: Q9WV56 Mouse

Unigene: 218418 Rat



產(chǎn)品圖片
Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-BMP9 (bs-6909R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 12/47 kD Observed band size: 50 kD
Sample: HepG2 Cell (Human) Lysate at 40 ug Primary: Anti-BMP9 (bs-6909R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 12/47 kD Observed band size: 50 kD
Paraformaldehyde-fixed, paraffin embedded (Rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (BMP9) Polyclonal Antibody, Unconjugated (bs-6909R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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