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Rabbit Anti-CCDC52  antibody (bs-7989R)  
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產(chǎn)品編號 bs-7989R
英文名稱 Rabbit Anti-CCDC52  antibody
中文名稱 卷曲螺旋結構域蛋白52抗體
別    名 Coiled coil domain containing protein 52; Coiled-coil domain-containing protein 52; FLJ26064; FLJ44949; SPICE_HUMAN; spice1; Spindle and centriole-associated protein 1; Spindle and centriole-associated protein.  
研究領域 細胞生物  免疫學  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 96kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CCDC52: 51-140/855 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. The gene encoding CCDC52 (Coiled-coil domain-containing protein 52), a 855 amino acid protein, exists on human chromosome 3.

Function:
Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis.

Subunit:
Interacts with CEP120

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome, centriole. Cytoplasm, cytoskeleton, spindle.

SWISS:
Q8N0Z3

Gene ID:
152185

Database links:

Entrez Gene: 152185 Human

Omim: 613447 Human

SwissProt: Q8N0Z3 Human

Unigene: 477144 Human



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