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Rabbit Anti-AGFG1  antibody (bs-8072R)  
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產(chǎn)品編號(hào) bs-8072R
英文名稱 Rabbit Anti-AGFG1  antibody
中文名稱 艾滋病病毒復(fù)制結(jié)合蛋白抗體
別    名 HIV 1 Rev binding protein; RAB; Rev/Rex activation domain-binding protein; RIP; AGFG1; AGFG1_HUMAN; Arf-GAP domain and FG repeats-containing protein 1; ArfGAP with FG repeats 1; HIV-1 Rev-binding protein; HRB; Nucleoporin like protein RIP; Nucleoporin-like protein RIP; Rev interacting protein; Rev-interacting protein.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)菌及病毒  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 58kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AGFG1: 276-380/562 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.

Function:
Required for vesicle docking or fusion during acrosomebiogenesis (By similarity). May play a role in RNA trafficking orlocalization. In case of infection by HIV-1, acts as a cofactor forviral Rev and promotes movement of Rev-responsiveelement-containing RNAs from the nuclear periphery to thecytoplasm. This step is essential for HIV-1 replication.

Subunit:
Interacts with EPS15R and EPS15. Interacts with FCHO1.

Subcellular Location:
Nucleus. Cytoplasmic vesicle.

Tissue Specificity:
Ubiquitously expressed.

Post-translational modifications:
O-glycosylated (By similarity).

Similarity:
Contains 1 Arf-GAP domain.

SWISS:
P52594

Gene ID:
3267

Database links:

Entrez Gene: 536149 Cow

Entrez Gene: 3267 Human

Entrez Gene: 15463 Mouse

Entrez Gene: 363266 Rat

Omim: 600862 Human

SwissProt: Q2TA45 Cow

SwissProt: P52594 Human

SwissProt: Q8K2K6 Mouse

SwissProt: Q4KLH5 Rat

Unigene: 352962 Human

Unigene: 392569 Mouse

Unigene: 433409 Mouse

Unigene: 3734 Rat



產(chǎn)品圖片
Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti- AGFG1 (bs-8072R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58kD Observed band size: 55 kD
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