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Rabbit Anti-RNF138  antibody (bs-9254R)  
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200ul/2800.00元
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產(chǎn)品編號(hào) bs-9254R
英文名稱 Rabbit Anti-RNF138  antibody
中文名稱 環(huán)指蛋白138抗體
別    名 E3 ubiquitin protein ligase RNF138; E3 ubiquitin-protein ligase RNF138; hNARF; HSD 4; HSD4; MGC8758; NARF; Nemo like kinase associated RING finger protein; Nemo-like kinase-associated RING finger protein; NLK associated RING finger protein; NLK-associated RING finger protein; RING finger protein 138; RN138_HUMAN; Rnf138; STRIN.  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat (predicted: Human,Mouse,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 28kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RNF138: 51-150/245 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.

Function:
E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.

Subunit:
Interacts with NLK.

Post-translational modifications:
Auto-ubiquitinated.

Similarity:
Contains 1 RING-type zinc finger.

SWISS:
Q8WVD3

Gene ID:
51444

Database links:

Entrez Gene: 51444 Human

Entrez Gene: 56515 Mouse

Entrez Gene: 94196 Rat

SwissProt: Q8WVD3 Human

SwissProt: Q9CQE0 Mouse

SwissProt: Q99PD2 Rat

Unigene: 302408 Human

Unigene: 253542 Mouse

Unigene: 6814 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (rat testis tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RNF138) Polyclonal Antibody, Unconjugated (bs-9254R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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