| 產(chǎn)品編號 | bs-9875R |
| 英文名稱 | Rabbit Anti-Salusin alpha antibody |
| 中文名稱 | 心血管調(diào)節(jié)肽Salusin-α抗體 |
| 別 名 | Prosalusin precursor; TOR2A; TORP1; Torsin 2A [Precursor]; Torsin family 2 member A; Torsin related protein 1; TOR2A_HUMAN. |
| 研究領(lǐng)域 | 心血管 免疫學(xué) 神經(jīng)生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Cow) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 33kDa |
| 細胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Salusin alpha: 51-150/321 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis; it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation. Subcellular Location: Secreted. Tissue Specificity: Isoform 1 is expressed ubiquitously, except in cardiac and endothelial tissues. Similarity: Belongs to the clpA/clpB family. Torsin subfamily. SWISS: Q5JU69 Gene ID: 27433 Database links: Entrez Gene: 27433 Human Omim: 608052 Human SwissProt: Q5JU69 Human Unigene: 444106 Human |
