| 產(chǎn)品編號(hào) | bs-9685R |
| 英文名稱(chēng) | Rabbit Anti-C1GALT1 antibody |
| 中文名稱(chēng) | N-乙酰半乳糖胺糖蛋白3、β-半乳糖轉(zhuǎn)移酶1抗體 |
| 別 名 | B3Gal T8; Beta 1 3 galactosyltransferase; C1GALT; Core 1 beta1 3 galactosyltransferase 1; Core 1 beta3 Gal T; Core 1 O glycan T synthase; Core 1 synthase glycoprotein N acetylgalactosamine 3 beta galactosyltransferase 1; Core 1 UDP galactose:N acetylgalactosamine alpha R beta 1 3 galactosyltransferase; Glycoprotein N acetylgalactosamine 3 beta galactosyltransferase 1; T synthase. |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 免疫學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 40kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C1GALT1: 171-270/363 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
C1GALT1 is a glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is synthesized by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended O-glycans in glycoproteins. C1GALT1 plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development. Function: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development. Subunit: Homodimer; disulfide-linked (By similarity). Interacts with the C1GALT1C1 chaperone; required for galactosyltransferase activity. Subcellular Location: Membrane. Tissue Specificity: Widely expressed. Highly expressed in kidney, heart, placenta and liver. Similarity: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. SWISS: Q9NS00 Gene ID: 56913 Database links: Entrez Gene: 56913 Human Omim: 610555 Human SwissProt: Q9NS00 Human |
