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Rabbit Anti-VGLUT1/BNP1  antibody (bs-11167R)  
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產(chǎn)品編號(hào) bs-11167R
英文名稱 Rabbit Anti-VGLUT1/BNP1  antibody
中文名稱 腦特異性鈉依賴無(wú)機(jī)磷轉(zhuǎn)運(yùn)蛋白抗體
別    名 BNPI; Brain specific Na (+) dependent inorganic phosphate cotransporter; Brain specific Na dependent inorganic phosphate cotransporter; Brain-specific Na(+)-dependent inorganic phosphate cotransporter; Slc17a7; Solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; Solute carrier family 17 member 7; Vesicular glutamate transporter 1; VGLU1_HUMAN; VGluT1.  
Specific References  (4)     |     bs-11167R has been referenced in 4 publications.
[IF=9.995] Qian Fang. et al. YTHDF1 phase separation triggers the fate transition of spermatogonial stem cells by activating the IκB-NF-κB-CCND1 axis. CELL REP. 2023 Apr 14;42(4):112403  IF ;  Mouse.  
[IF=2.11] Fujita, Yu, et al. "Expression of MEGF10 in cholinergic and glutamatergic neurons." Neuroscience Letters (2017).  IHC ;  Mouse.  
[IF=1.931] Wan, Dong-Feng. et al. Late Exercise Preconditioning Regulates BNP Increasing to Assist the Cardioprotection via Up-Regulation of NPR-A and Down-Regulation of NPR-C in Rat Myocardium. Int J Pept Res Ther. 2022 Jan;28(1):1-11  WB,IHC ;  Rat.  
[IF=0] Canhong Wang. et al. Agarwood essential oil inhalation exerts antianxiety and antidepressant effects via the regulation of Glu/GABA system homeostasis. BIOMED REP. 2023 Feb;18(2):1-11  WB ;  Mouse.  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  細(xì)胞骨架  細(xì)胞膜蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human)
產(chǎn)品應(yīng)用 WB=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 62kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VGLUT1/BNP1: 301-400/560 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 BNPI; Brain specific Na (+) dependent inorganic phosphate cotransporter; Brain specific Na dependent inorganic phosphate cotransporter; Brain-specific Na(+)-dependent inorganic phosphate cotransporter; Slc17a7; Solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; Solute carrier family 17 member 7; Vesicular glutamate transporter 1; VGLU1_HUMAN; VGluT1.

Function:
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.

Subcellular Location:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein (Potential). Cell junction, synapse, synaptosome.

Tissue Specificity:
Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe.

Similarity:
Belongs to the major facilitator superfamily.
Sodium/anion cotransporter family. VGLUT subfamily.

SWISS:
Q9P2U7

Gene ID:
57030

Database links:

Entrez Gene: 518849 Cow

Entrez Gene: 57030 Human

Entrez Gene: 72961 Mouse

Entrez Gene: 116638 Rat

Omim: 605208 Human

SwissProt: A4FV52 Cow

SwissProt: Q9P2U7 Human

SwissProt: Q3TXX4 Mouse

SwissProt: Q62634 Rat

Unigene: 375616 Human

Unigene: 255631 Mouse

Unigene: 10267 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded Rat Cerebellum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with VGLUT1/BNP1 Polyclonal Antibody, Unconjugated (bs-11167R) at 1:100 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Rat Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with VGLUT1/BNP1 Polyclonal Antibody, Unconjugated (bs-11167R) at 1:100 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with VGLUT1/BNP1 Polyclonal Antibody, Unconjugated (bs-11167R) at 1:100 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit, SP-0023) and DAB (C-0010) staining.
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