| 產(chǎn)品編號 | bs-12175R |
| 英文名稱 | Rabbit Anti-KCNG3 antibody |
| 中文名稱 | 電壓門控性鉀通道蛋白亞基KV6.3抗體 |
| 別 名 | KCNG 3; Kcng3; KCNG3_HUMAN; KV10.1; Kv10.1a; Kv10.1b; KV6.3; OTTHUMP00000201478; OTTHUMP00000201479; Potassium voltage gated channel subfamily G member 3; Potassium voltage-gated channel subfamily G member 3; Voltage gated potassium channel 6.3; Voltage gated potassium channel Kv10.1; Voltage gated potassium channel subunit Kv10.1; Voltage gated potassium channel subunit Kv6.3; Voltage gated potassium channel subunit Kv6.4; Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 通道蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,GuineaPig,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 50kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KCNG3: 251-350/436 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]. Function: Potassium channel subunit. Modulates channel activity. Subunit: Heteromultimer with KCNB1, KCNC1 and KCNF1. Does not form homomultimers. Subcellular Location: Cell membrane. Membrane. Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1. Tissue Specificity: Detected in many parts of the brain with the exception of the cerebellum, in testis, pancreas, lung, kidney, ovary, small intestine, colon, thymus, adrenal gland and spinal cord. Similarity: Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.3/KCNG3 sub-subfamily. SWISS: Q8TAE7 Gene ID: 170850 Database links: Entrez Gene: 170850 Human Entrez Gene: 225030 Mouse Omim: 606767 Human SwissProt: Q8TAE7 Human SwissProt: P59053 Mouse Unigene: 352633 Human Unigene: 223506 Mouse Unigene: 82689 Rat |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Human Jurkat cell Lysates
Lane 2: Human SH-SY5Y cell Lysates
Primary: Anti-KCNG3 (bs-12175R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 50kDa
Observed band size: 110kDa
|
