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Rabbit Anti-ZFP100 / ZNF473  antibody (bs-12242R)  
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產(chǎn)品編號(hào) bs-12242R
英文名稱 Rabbit Anti-ZFP100 / ZNF473  antibody
中文名稱 鋅指蛋白100/鋅指蛋白473抗體
別    名 HZFP100; Zfp 100; Zfp-100; Zinc finger protein 100 homolog; Zinc finger protein 473; zinc finger protein ZFP100; ZN473_HUMAN.  
研究領(lǐng)域 轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 100kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZFP100/ZNF473: 701-830/871 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.

Function:
Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.

Subunit:
Interacts with the SLBP/pre-mRNA complex but not with SLBP alone. Interacts with LSM11 in a U7 snRNP-dependent manner.

Subcellular Location:
Nucleus. Stable component of Cajal bodies (CBs). Colocalizes with SMN, coilin and U7 snRNA.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 20 C2H2-type zinc fingers.
Contains 1 KRAB domain.

SWISS:
Q8WTR7

Gene ID:
25888

Database links:

Entrez Gene: 25888 Human

SwissProt: Q8WTR7 Human

Unigene: 440553 Human



產(chǎn)品圖片
Sample: Bone (mouse) Lysate at 40 ug Primary: Anti- NF473(bs-12242R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 100 kD Observed band size: 100 kD
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