来一水AV@lysav|亚洲AV无码片VR一区二区三区 |国产亚洲精久久久久久无码|视色4se成人午夜精品久久

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
精品无码黑人又粗又大又长|亚洲精品无码MV在线观看网站|av亚洲国产小电影
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-nNOS  antibody (bs-10197R)  
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-10197R
英文名稱 Rabbit Anti-nNOS  antibody
中文名稱 一氧化氮合成酶-1(神經(jīng)型)抗體
別    名 NOS1_HUMAN; Nitric oxide synthase, brain; NOS1; EC:1.14.13.39; Constitutive NOS; N NOS; N-NOS; NC-NOS; NOS type I; Neuronal NOS (N-NOS; nNOS); Peptidyl-cysteine S-nitrosylase NOS1; bNOS; neuronal Nitric Oxide Synthase;   
Specific References  (3)     |     bs-10197R has been referenced in 3 publications.
[IF=12.35] Baruteau et al. Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer. (2018) Nat.Commun. 9:3505  IHC ;  Mouse.  
[IF=4.492] Rocha-Ferreira et al. Immediate Remote Ischemic Postconditioning Reduces Brain Nitrotyrosine Formation in a Piglet Asphyxia Model. (2016) Oxid.Med.Cell.Longe. 2016:5763743  IHC-P ;  Pig.  
[IF=0.18] Fu, G., et al. "Penile erectile dysfunction after brachial plexus root avulsion injury in rats." Neural Regeneration Research 9.20 (2014): 1839.  IHC-F ;  Rat.  
研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  合成與降解  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse (predicted: Rat,Pig,Sheep,Cow,Chicken,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 130kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human nNos/NOS-1: 601-700/1434 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011].

Function:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.

Subunit:
Homodimer. Interacts with DLG4; the interaction possibly being prevented by the association between NOS1 and CAPON. Forms a ternary complex with CAPON and RASD1. Forms a ternary complex with CAPON and SYN1. Interacts with ZDHHC23. Interacts with NOSIP; which may impair its synaptic location (By similarity). Interacts with HTR4. Interacts with VAC14 (By similarity). Interacts with SLC6A4.

Subcellular Location:
Cell membrane, sarcolemma; Peripheral membrane protein. Cell projection, dendritic spine. Note=In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity).

Tissue Specificity:
Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis, lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the platelets. Isoform 3 is expressed only in testis. Isoform 4 is detected in testis, skeletal muscle, lung, and kidney, at low levels in the brain, but not in the heart and adrenal gland.

Post-translational modifications:
Ubiquitinated; mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro).

Similarity:
Belongs to the NOS family.
Contains 1 FAD-binding FR-type domain.
Contains 1 flavodoxin-like domain.
Contains 1 PDZ (DHR) domain.

SWISS:
P29475

Gene ID:
4842

Database links:

Entrez Gene: 4842 Human

Omim: 163731 Human

SwissProt: P29475 Human

Unigene: 654410 Human

Unigene: 684465 Human

Unigene: 684466 Human

Unigene: 684467 Human



一氧化氮合成酶-1催化生物體內(nèi)一氧化氮(NO)生成的酶。分神經(jīng)型一氧化氮合成的酶(nNOS or NOS1)、誘導(dǎo)型一氧化氮合成的酶(iNOS or NOS2)、內(nèi)皮型一氧化氮合成的酶(eNOS or NOS3)。此抗體識別分子量為150kDa的神經(jīng)型一氧化氮合成的酶。
產(chǎn)品圖片
Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti- nNOS (bs-10197R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 130 kD Observed band size: 150 kD
Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti-nNOS (bs-10197R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 130 kD Observed band size: 130 kD
Sample: Hela(Human) Cell Lysate at 30 ug MCF-7(Human) Cell Lysate at 30 ug A549(Human) Cell Lysate at 30 ug RAW246.7 (Mouse) Cell Lysate at 30 ug Primary: Anti-nNOS (bs-10197R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 130 kD Observed band size: 130 kD
Paraformaldehyde-fixed, paraffin embedded (Mouse testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (nNOS) Polyclonal Antibody, Unconjugated (bs-10197R ) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
版權(quán)所有 2004-2026 www.73327.net 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
亚洲午夜久久久久久久久电影网| 亚洲男人第一无码AV网站| 播五月色五月开心五月网| 久久久久免费精品国产| 国产在线偷观看免费观看| 色偷偷噜噜噜亚洲男人| 国产精品扒开腿做爽爽爽A片小说 久久久久亚洲AV无码A片下载 | 国产精品久久午夜福利| 东京热无码av男人的天堂| 国产成人动态图视频| 99国产在线视频网站| 伦理精品一区二区三区| 国产探花在线精品一区二区| 日本熟女精品一区二区三区 | 色噜噜亚洲丰满熟妇av片| 最近免费中文字幕大全免费版视频| 99精品视频在线观看免费| 国产精品欧美激情melody| 国产H视频在线观看| 精品久久久久久无码免费| 精品乱子伦一区二区三区| 中国杭州少妇XXXX做受| 国产福利jk视频在线观看| 男阳茎进女阳道视频大全| 亚洲AV无码久久寂寞少妇| 人妻人妻与人妻人妻AV| 色综合久久综合中文综合网 | 成人免费视频一区二区| 亚洲日韩欧美一区二区三区| 午夜精品久久久久久99影视| 熟妇女人妻丰满少妇中文字幕| 亚洲精品1卡2卡3卡| 亚洲影院色无极手机版| 亚洲 自拍 另类小说综合图区| 日韩亚洲欧洲一区二区三区| 国产精品白浆一区二区三区| 波多野42部无码喷潮在线| 一边吃奶一边添P好爽故事| 天天做天天爱夜夜爽| 午夜一区二区国产好的精华液| 午夜福利网站久久久久久|