| 產(chǎn)品編號 | bs-15397R |
| 英文名稱 | Rabbit Anti-CRAT antibody |
| 中文名稱 | 肉毒堿O-乙酰基轉(zhuǎn)移酶 |
| 別 名 | CACP_HUMAN; Carnitine acetylase; Carnitine acetyltransferase; Carnitine O acetyltransferase; Carnitine O-acetyltransferase; CAT; CAT1; CrAT; |
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Specific References (1) | bs-15397R has been referenced in 1 publications.
[IF=2.19] Jiang, Qixiao, et al. "Changes in the levels of l-carnitine, acetyl-l-carnitine and propionyl-l-carnitine are involved in perfluorooctanoic acid induced developmental cardiotoxicity in chicken embryo." Environmental Toxicology and Pharmacology 48 (2016): 116-124. WB ; Chicken.
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| 研究領(lǐng)域 | 心血管 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 脂蛋白 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Chicken) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 71kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CRAT: 301-400/626 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
CRAT is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Two transcript variants encoding different isoforms have been found for this gene. Function: Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria. Subunit: Monomer. Subcellular Location: Endoplasmic reticulum (Potential). Peroxisome (Potential). Mitochondrion inner membrane; Peripheral membrane protein; Matrix side (Potential). Isoform 1: Mitochondrion (Potential). Isoform 2: Peroxisome (Potential). Tissue Specificity: Mostly in skeletal muscle, less in heart, liver and pancreas, only weakly detectable in brain, placenta, lung and kidney. Similarity: Belongs to the carnitine/choline acetyltransferase family. SWISS: P43155 Gene ID: 6541 Database links: Entrez Gene: 6541 Human Entrez Gene: 11987 Mouse Omim: 104615 Human SwissProt: P30825 Human SwissProt: Q09143 Mouse Unigene: 14846 Human Unigene: 275489 Mouse |
| 產(chǎn)品圖片 |
Sample:
muscle (Mouse) Lysate at 40 ug
heart (Mouse) Lysate at 40 ug
Primary: Anti-CRAT(bs-15397R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 71kD
Observed band size: 71kD
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