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Rabbit Anti-CPEB2  antibody (bs-14019R)  
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產(chǎn)品編號(hào) bs-14019R
英文名稱 Rabbit Anti-CPEB2  antibody
中文名稱 細(xì)胞質(zhì)多聚腺苷酸結(jié)合蛋白2抗體
別    名 CPE binding protein 2; CPE BP2; CPEB 2; CPEBP2; Cytoplasmic polyadenylation element binding protein 2; hCPEB 2; hCPEB2; CPEB2_HUMAN.  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  結(jié)合蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Pig,Sheep,Cow,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 65kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CPEB2: 481-589/589 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
CPEB2, (Cytoplasmic polyadenylation element-binding protein 2), belongs to the RRM CPEB family and contains 2 RRM (RNA recognition motif) domains. It may bind poly(U) RNA oligomers. It may play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. There are 7 named isoforms [FASTA] produced by alternative splicing.

Subcellular Location:
Cytoplasmic

Similarity:
Belongs to the RRM CPEB family.
Contains 2 RRM (RNA recognition motif) domains.

SWISS:
Q7Z5Q1

Gene ID:
132864

Database links:

Entrez Gene: 132864 Human

Entrez Gene: 231207 Mouse

Entrez Gene: 360949 Rat

Omim: 610605 Human

SwissProt: Q7Z5Q1 Human

SwissProt: Q812E0 Mouse

Unigene: 656937 Human

Unigene: 162283 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CPEB2) Polyclonal Antibody, Unconjugated (bs-14019R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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