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Rabbit Anti-DEFB112  antibody (bs-14245R)  
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產(chǎn)品編號(hào) bs-14245R
英文名稱 Rabbit Anti-DEFB112  antibody
中文名稱 防御素β-112/β-defensin 112抗體
別    名 beta 112; Beta-defensin 112; Beta-defensin 12; DB112_HUMAN; DEFB-12; DEFB112; Defensin.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  發(fā)育生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 13kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DEFB112: 41-113/113 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 beta-defensins are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, beta-defensins are developmentally regulated. The family of beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many beta-defensins also are involved in sperm maturation and capacitation. beta-defensin 112 is a 113 amino acid secreted protein that has antibacterial activity.

Function:
Has antibacterial activity.

Subcellular Location:
Secreted.

Similarity:
Belongs to the beta-defensin family.

SWISS:
Q30KQ8

Gene ID:
245915

Database links:

Entrez Gene: 245915 Human

SwissProt: Q30KQ8 Human

Unigene: 571092 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Human glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DEFB112) Polyclonal Antibody, Unconjugated (bs-14245R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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