產(chǎn)品編號(hào) | bs-14347R |
英文名稱(chēng) | Rabbit Anti-DMRT2 antibody |
中文名稱(chēng) | DMRT2蛋白抗體 |
別 名 | DMRT2; DMRT2_HUMAN; Doublesex and mab 3 related transcription factor 2; Doublesex- and mab-3-related transcription factor 2; Doublesex-like 2 protein; DSXL 2; DSXL-2; DSXL2; terra like protein. |
研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Sheep,Cow) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 62kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DMRT2: 151-250/561 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010] Function: Expressed in testis, kidney and skeletal muscle. Subcellular Location: Nucleus. Similarity: Belongs to the DMRT family. Contains 1 DM DNA-binding domain. SWISS: B1ANC0 Gene ID: 10655 Database links: Entrez Gene: 10655 Human Entrez Gene: 226049 Mouse Omim: 604935 Human SwissProt: B1ANC0 Human SwissProt: Q9Y5R5 Human SwissProt: Q3USI4 Mouse SwissProt: Q3USI7 Mouse SwissProt: Q8BG36 Mouse SwissProt: Q8K185 Mouse Unigene: 59506 Human Unigene: 11448 Rat |
產(chǎn)品圖片 | |