產(chǎn)品編號 | bs-14495R |
英文名稱 | Rabbit Anti-EBP2 antibody |
中文名稱 | EB病毒核抗原1結(jié)合蛋白2抗體 |
別 名 | EBNA1-binding protein 2; EBNA1 binding protein 2; ebna1bp2; EBP2; EBP2_HUMAN; NOBP; nuclear FGF3 binding protein; Nucleolar protein p40; P40; Probable rRNA processing protein EBP2; Probable rRNA-processing protein ebp2. |
研究領(lǐng)域 | 腫瘤 細(xì)菌及病毒 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 36kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human EBP2 : 201-300/306 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The replication and stable maintenance of latent Epstein-Barr virus DNA episomes in human cells requires only one viral protein, Epstein-Barr nuclear antigen 1 (EBNA1). EBNA1 binding protein 2, also designated p40/EBP2, is a nuclear protein required for the processing of the 27S pre-rRNA. EBP2 is highly conserved across species and is ubiquitously expressed in human tissues, especially myelogenous leukemia K-562. EBP2 specifically interacts with EBNA1, supporting the long-term maintenance of Epstein-Barr virus plasmids in human cells. The EBNA1-EBP2 complex is important for the stable segregation of Epstein-Barr virus episomes during cell division. Function: Required for the processing of the 27S pre-rRNA Subcellular Location: Nucleus > nucleolus. Tissue Specificity: Ubiquitous. Similarity: Belongs to the EBP2 family. SWISS: Q99848 Gene ID: 10969 Database links: Entrez Gene: 10969 Human Omim: 614443 Human SwissProt: Q99848 Human Unigene: 346868 Human |