| 產(chǎn)品編號 | bs-14586R |
| 英文名稱 | Rabbit Anti-EML1 antibody |
| 中文名稱 | EML1蛋白抗體 |
| 別 名 | echinoderm microtubule associated protein like 1; Echinoderm microtubule-associated protein-like 1; ELP79; EMAL1_HUMAN; EMAP; EMAP-1; EMAPL; Eml1; FLJ45033; HuEMAP; HuEMAP-1. |
| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 90kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EML1: 751-815/815 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic. Subcellular Location: Cytoplasm; cytoskeleton. Tissue Specificity: Ubiquitous; expressed in most tissues with the exception of thymus and peripheral blood lymphocytes. Similarity: Belongs to the WD repeat EMAP family. Contains 10 WD repeats. SWISS: O00423 Gene ID: 2009 Database links: Entrez Gene: 2009 Human Entrez Gene: 68519 Mouse GenBank: NP_001008707 Human Omim: 602033 Human SwissProt: O00423 Human SwissProt: Q05BC3 Mouse Unigene: 12451 Human Unigene: 236645 Mouse Unigene: 211693 Rat |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with EML1 polyclonal antibody, unconjugated (bs-14586R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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