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Rabbit Anti-KTEL1  antibody (bs-16861R)  
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產(chǎn)品編號 bs-16861R
英文名稱 Rabbit Anti-KTEL1  antibody
中文名稱 骨髓增生異常綜合征相關蛋白抗體
別    名 C3orf9; CAP10 like 46 kDa protein; CAP10 like protein, 46 kDa; CLP46; hCLP46; KDELC family like 1; KDELCL1; KTEL (Lys Tyr Glu Leu) containing 1; KTEL motif containing protein 1; KTELC1; MDS010; MDSRP; myelodysplastic syndromes relative protein; POGLUT1; protein O glucosyltransferase 1; Rumi; x 010 protein.  
研究領域 細胞生物  免疫學  發(fā)育生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow,Dog,Horse)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 43kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KTEL1: 201-300/392 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 CLP46 is a KTEL motif-containing protein that belongs to the CAP10 family. The KTEL motif at the C-terminus of CLP46 is an endoplasmic reticulum (ER) retention signal which localizes the CLP46 protein to the lumen of the ER. CLP46 is thought to promote cell proliferation and is also believed to be involved with hepatic functions. The Drosophila protein rumi, a CAP10 protein and likely similar in function to CLP46, uses glucosylation to act as a Notch signaling regulator. Expressed in varying degrees in most adult tissue, CLP46 is especially abundant in the liver. CLP46 is not expressed in detectable levels in colon, thymus or small intestine. Human CLP46 shares 94% and 91% sequence similarity with its bovine and mouse homologs, respectively.

Function:
UDP-glucosyltransferase.

Subcellular Location:
Endoplasmic reticulum lumen.

Tissue Specificity:
Expressed in most adult tissues at different intensities. Abundantly expressed in liver. Expressed also in brain, heart, skeletal muscle, spleen, kidney, placenta, lung and peripheral blood leukocyte. Not detectable in colon, thymus and small intestine.

Similarity:
Belongs to the glycosyltransferase 90 family.

SWISS:
Q8NBL1

Gene ID:
56983

Database links:

Entrez Gene: 56983 Human

Entrez Gene: 224143 Mouse

Entrez Gene: 288091 Rat

SwissProt: Q8NBL1 Human

SwissProt: Q8BYB9 Mouse



產(chǎn)品圖片
Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-KTEL1 (bs-16861R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 43 kD
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