| 產(chǎn)品編號 | bs-17054R |
| 英文名稱 | Rabbit Anti-KIF26B antibody |
| 中文名稱 | 驅(qū)動蛋白家族成員26B抗體 |
| 別 名 | FLJ10157; FLJ10157; KI26B_HUMAN; KIF26B; Kinesin-like protein KIF26B. |
| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 信號轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 224kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KIF26B: 221-320/2108 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF26B (kinesin family member 26B) is a 2,108 amino acid protein that contains one kinesin-motor domain and belongs to the kinesin-like protein family. The kinesin-motor domain is responsible for the ATP-dependent movement of KIF26B across microtubules. KIF26B regulates the adhesion of mesenchymal cells in contact with ureteric buds, making it essential for kidney development. KIF26B is also thought to play a role in embryogenesis, specifically in the development of limbs, face and somites. KIF26B localizes to the cytoplasm and exists as two alternatively splices isoforms. The gene encoding KIF26B is located on human chromosome 1q43. Subcellular Location: Cytoplasm > cytoskeleton. Similarity: Belongs to the kinesin-like protein family. KIF26 subfamily. Contains 1 kinesin-motor domain. SWISS: Q2KJY2 Gene ID: 55083 Database links: Entrez Gene: 55083 Human Omim: 614026 Human SwissProt: Q2KJY2 Human Unigene: 368096 Human |
