| 產(chǎn)品編號(hào) | bs-17366R |
| 英文名稱 | Rabbit Anti-HOXC11 antibody |
| 中文名稱 | 同源盒蛋白C11抗體 |
| 別 名 | Homeo box C11; Homeobox C11; Homeobox protein Hox C11; Homeobox protein Hox-3H; Homeobox protein Hox-C11; HOX3H; HOXC11; HXC11_HUMAN; MGC4906. |
| 研究領(lǐng)域 | 細(xì)胞生物 結(jié)合蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Sheep,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 34kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HOXC11: 211-304/304 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [provided by RefSeq, Jul 2008] Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to a promoter element of the lactase-phlorizin hydrolase gene. Subcellular Location: Nucleus. Similarity: Belongs to the Abd-B homeobox family. Contains 1 homeobox DNA-binding domain. SWISS: O43248 Gene ID: 3227 Database links: Entrez Gene: 3227 Human Omim: 605559 Human SwissProt: O43248 Human SwissProt: P31313 Mouse Unigene: 127562 Human Unigene: 37692 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Human HepG2 cell lysates
Lane 2: Human 293T cell lysates
Lane 3: Human HeLa cell lysates
Primary: Anti-HOXC11 (bs-17366R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 34 kDa
Observed band size: 36 kDa
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