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Rabbit Anti-SPATS2  antibody (bs-17638R)  
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100ul/1980.00元
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產(chǎn)品編號 bs-17638R
英文名稱 Rabbit Anti-SPATS2  antibody
中文名稱 富含絲氨酸精子發(fā)生相關(guān)蛋白2抗體
別    名 Nbla00526; p59scr; SCR59; Serine-rich spermatocytes and round spermatid 59 kDa protein; SPAS2_HUMAN; SPATA10; Spats2; Spermatogenesis-associated serine-rich protein 2.  
研究領域 細胞生物  免疫學  發(fā)育生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 60kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPATS2: 321-420/545 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 SPATS2 is a 545 amino acid cytoplasmic protein that belongs to the SPATS2 family. The gene encoding SPATA10 maps to human chromosome 12q13.12 and mouse chromosome 15 F1. Chromosome 12 makes up about 4.5% of the human genome and is linked to a number of skeletal deformities, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism. It is most severe in cases of complete trisomy.

Subunit:
Belongs to the SPATS2 family.

Subcellular Location:
Cytoplasm.

SWISS:
Q86XZ4

Gene ID:
65244

Database links:

Entrez Gene: 65244 Human

Omim: 611667 Human

SwissProt: Q86XZ4 Human

Unigene: 654826 Human



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