| 產(chǎn)品編號 | bs-18551R |
| 英文名稱 | Rabbit Anti-ZCCHC24/C10orf56 antibody |
| 中文名稱 | 10號染色體開放閱讀框56抗體 |
| 別 名 | C10orf56; Chromosome 10 open reading frame 56; Zinc finger CCHC domain-containing protein 24; Zinc finger, CCHC domain containing 24. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Zebrafish,Chicken,Horse,Danio) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 27kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZCCHC24/C10orf56: 101-200/241 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
ZCCHC24 is a 241 amino acid protein that contains one CCHC-type zinc finger, suggesting a role in transcriptional regulation. The gene encoding ZCCHC24 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious. SWISS: Q8N2G6 Gene ID: 219654 Database links: Entrez Gene: 219654 Human Entrez Gene: 71918 Mouse SwissProt: Q8N2G6 Human SwissProt: B2RVL6 Mouse Unigene: 523080 Human Unigene: 41904 Mouse Unigene: 44060 Rat |
| 產(chǎn)品圖片 |
Sample: Hela (human) Cell Lysate at 40 ug
Primary: Anti-ZCCHC24/C10orf56 (bs-18551R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27 kD
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