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Rabbit Anti-PRPSAP2  antibody (bs-19410R)  
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產(chǎn)品編號(hào) bs-19410R
英文名稱 Rabbit Anti-PRPSAP2  antibody
中文名稱 磷酸核糖焦磷酸合成酶相關(guān)蛋白2抗體
別    名 41 kDa phosphoribosypyrophosphate synthetase associated protein; 41 kDa phosphoribosypyrophosphate synthetase-associated protein; KPRB; KPRB_HUMAN; MGC117304; MGC126719; MGC126721; PAP41; Phosphoribosyl pyrophosphate synthase-associated protein 2; Phosphoribosyl pyrophosphate synthetase associated protein 2; PRPP synthase-associated protein 2; PRPP synthetase associated protein 2;   
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Rabbit,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 41kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRPSAP2: 1-100/369 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

Function:
Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the ribose-phosphate pyrophosphokinase family.

SWISS:
O60256

Gene ID:
5636

Database links:

Entrez Gene: 5636 Human

Entrez Gene: 212627 Mouse

Entrez Gene: 117272 Rat

Omim: 603762 Human

SwissProt: O60256 Human

SwissProt: Q8R574 Mouse

SwissProt: O08618 Rat

Unigene: 632236 Human

Unigene: 27703 Mouse

Unigene: 2681 Rat



產(chǎn)品圖片
Sample: A431(Human) Cell Lysate at 40 ug Primary: Anti-aPRPSAP2 (bs-19410R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kD Observed band size: 41 kD
Paraformaldehyde-fixed, paraffin embedded (Mouse liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PRPSAP2) Polyclonal Antibody, Unconjugated (bs-19410R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PRPSAP2) Polyclonal Antibody, Unconjugated (bs-19410R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PRPSAP2) Polyclonal Antibody, Unconjugated (bs-19410R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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