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Rabbit Anti-BVDV E2  antibody (bs-20022R)  
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產(chǎn)品編號(hào) bs-20022R
英文名稱 Rabbit Anti-BVDV E2  antibody
中文名稱 牛病毒性腹瀉病毒1型E2蛋白抗體
別    名 polyprotein [Bovine viral diarrhea virus 1]; POLG_BVDVN; Envelope glycoprotein E2; BVDV Envelope glycoprotein E2; PestiV1gp1 polyprotein [ Bovine viral diarrhea virus 1 ].  牛病毒性腹瀉病毒1型;
Specific References  (2)     |     bs-20022R has been referenced in 2 publications.
[IF=8.786] Mi Shijiang. et al. Characterization of monoclonal antibodies that specifically differentiate field isolates from vaccine strains of classical swine fever virus. FRONT IMMUNOL. 2022 Jul;0:3835  IFA ;  Pig.  
[IF=5.913] Cheng, Jinghua. et al. Coinfection with PEDV and BVDV induces inflammatory bowel disease pathway highly enriched in PK-15 cells. VIROL J. 2022 Dec;19(1):1-12  IF, WB ;  Pig.  
研究領(lǐng)域 細(xì)菌及病毒  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: BVDV)
產(chǎn)品應(yīng)用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45kDa
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinded BVDV Envelope glycoprotein E2: full length protein 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Initial binding to target cell probably involves interaction of E(rns) with glycosaminoglycans. E1 and/or E2 are responsible of cell attachment with CD46 and subsequent fusion after internalization of the virion by endocytosis (Probable).
P7 forms a leader sequence to properly orient NS2 in the membrane.
Uncleaved NS2-3 is required for production of infectious virus.
NS2 protease seems to play a vital role in viral RNA replication control and in the pathogenicity of the virus.
NS3 displays three enzymatic activities: serine protease, NTPase and RNA helicase.
NS4A is a cofactor for the NS3 protease activity.
RNA-directed RNA polymerase NS5 replicates the viral (+) and (-) genome.

SWISS:
P19711

Gene ID:
1489735

Database links:
Entrez Gene: 1489735 BVDV

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