| 產(chǎn)品編號 | bs-20082R |
| 英文名稱 | Rabbit Anti-SMCP antibody |
| 中文名稱 | 精子線粒體相關(guān)富含半胱氨酸蛋白抗體 |
| 別 名 | HSMCSGEN1; MCS; MCSP; MCSP_HUMAN; Mitochondrial capsule selenoprotein; SMCP; Sperm mitochondria associated cysteine rich protein; Sperm mitochondrial-associated cysteine-rich protein. |
| 研究領(lǐng)域 | 細胞生物 發(fā)育生物學(xué) 干細胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 13kDa |
| 細胞定位 | 細胞漿 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SMCP: 31-116/116 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
SMCP is a 116 amino acid cytoplasmic protein that is found in the outer capsule that is associated with sperm mitochondria. Expressed specifically in spermatids of seminiferous tubules, SMCP is thought to be involved in the organization and stabilization of the helical sheath structure and may play a role in overall sperm motility. SMCP has a short N-terminal segment, a C-terminal lysine and several internal cysteines. Defects in the gene encoding SMCP may be a cause of male infertility due to both reduced sperm motility and an inability to pierce the zona pellucida of the female egg. Function: Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida. Subcellular Location: Cytoplasm. Mitochondrion membrane. Becomes associated with the spermatid mitochondrion capsule at step 16 of spermatogenesis. Tissue Specificity: Testis. Is selectively expressed in the spermatids of seminiferous tubules. SWISS: P49901 Gene ID: 4184 Database links: Entrez Gene: 4184 Human Omim: 601148 Human SwissProt: P49901 Human Unigene: 111850 Human |
