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Rabbit Anti-SLITL2  antibody (bs-21034R)  
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產(chǎn)品編號(hào) bs-21034R
英文名稱 Rabbit Anti-SLITL2  antibody
中文名稱 縫隙樣蛋白Slitl2抗體
別    名 2610528G05Rik; PRO1282; PRO357; Protein slit-like 2; Slit like 2; Slitl2; UNQ314; Vasn; VASN_HUMAN; Vasorin.  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 72kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLITL2: 451-550/673 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 VASN (Vasorin) is a Protein Coding gene. GO annotations related to this gene include transforming growth factor beta binding.

Function:
May act as an inhibitor of TGF-beta signaling.

Subunit:
Interacts with TGFB1, TGFB2 and TGFB3.

Subcellular Location:
Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.

Post-translational modifications:
N-glycosylated. N-glycan heterogeneity at Asn-117: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major), Hex6HexNAc5 (minor) and dHex1Hex6HexNAc5 (minor).

Similarity:
Contains 1 EGF-like domain.
Contains 1 fibronectin type-III domain.
Contains 10 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

SWISS:
Q6EMK4

Gene ID:
114990

Database links:

Entrez Gene: 114990 Human

Entrez Gene: 246154 Mouse

Entrez Gene: 679921 Rat

Omim: 608843 Human

SwissProt: Q6EMK4 Human

SwissProt: Q9CZT5 Mouse

Unigene: 372579 Human

Unigene: 482140 Mouse

Unigene: 198255 Rat



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