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Rabbit Anti-PLP2  antibody (bs-12733R)  
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產(chǎn)品編號 bs-12733R
英文名稱 Rabbit Anti-PLP2  antibody
中文名稱 蛋白脂質(zhì)蛋白2抗體
別    名 A4; A4 differentiation dependent protein; A4-LSB; A4LSB; differentiation dependent protein A4; Differentiation-dependent protein A4; Intestinal membrane A4 protein; MGC126187; PLP2; PLP2_HUMAN; proteolipid protein 2 (colonic epithelium enriched); Proteolipid protein 2.  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導  細胞周期蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 17kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PLP2: 1-100/152 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked mental retardation. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010]

Function:
May play a role in cell differentiation in the intestinal epithelium.

Subcellular Location:
Membrane.

Tissue Specificity:
Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt.

Similarity:
Contains 1 MARVEL domain.

SWISS:
Q04941

Gene ID:
5355

Database links:

Entrez Gene: 5355 Human

Omim: 300112 Human

SwissProt: Q04941 Human

Unigene: 77422 Human



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