| 產(chǎn)品編號(hào) | bs-21289R |
| 英文名稱(chēng) | Rabbit Anti-RBM15B antibody |
| 中文名稱(chēng) | RNA結(jié)合蛋白15B抗體 |
| 別 名 | 1810017N16Rik; Chromosome 3p21.1 gene sequence; HUMAGCGB; huOTT3; One twenty two protein 3; One-twenty two protein 3; OTT3; Putative RNA binding protein 15B; Putative RNA-binding protein 15B; RB15B_HUMAN; RBM15B; RGD1305937; RNA binding motif protein 15B; RNA-binding motif protein 15B. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 結(jié)合蛋白 表觀(guān)遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 97kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RBM15B: 581-680/890 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009] Function: May function in the regulation of alternative or illicit splicing. Subcellular Location: Nucleus > nucleoplasm. Colocalizes with BMLF1 in the nucleus. Localized in the nucleoplasm with a granular staining pattern and excluded from the nucleoli. Tissue Specificity: Ubiquitously expressed. Similarity: Belongs to the RRM Spen family. Contains 3 RRM (RNA recognition motif) domains. Contains 1 SPOC domain. SWISS: Q8NDT2 Gene ID: 109095 Database links: Entrez Gene: 29890 Human Entrez Gene: 109095 Mouse Omim: 612602 Human SwissProt: Q8NDT2 Human SwissProt: Q6PHZ5 Mouse Unigene: 118738 Human Unigene: 431589 Mouse |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Human stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RBM15B) Polyclonal Antibody, Unconjugated (bs-21289R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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