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Rabbit Anti-CXCL10/IP10  antibody (bs-23238R)  
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產(chǎn)品編號 bs-23238R
英文名稱 Rabbit Anti-CXCL10/IP10  antibody
中文名稱 CXCL10趨化因子10/干擾素誘導(dǎo)蛋白10抗體
別    名 10 kDa interferon gamma induced protein; C7; Chemokine (C X C motif) ligand 10; Chemokine CXC motif ligand 10; Crg 2; CRG2; CXCL 10; CXCL10; Gamma IP10; gIP 10; GIP10; IFI 10; IFI10; INP 10; INP10; Interferon activated gene 10; Interferon gamma induced cell line; Interferon inducible cytokine IP 10; MOB1; SCYB 10; SCYB10; Small inducible cytokine B10; Small inducible cytokine B10 precursor; Small inducible cytokine subfamily B (Cys X Cys) member 10; Gamma-IP-10.  
Specific References  (1)     |     bs-23238R has been referenced in 1 publications.
[IF=4.493] Fan Jiahui. et al. Study on the Correlation between Interleukin-27 and CXCL10 in Pulmonary Tuberculosis. J IMMUNOL RES. 2022;2022:2932837  IHC ;  Human.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  生長因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 10kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CXCL10/IP10: 29-70/98 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020]

Function:
Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.

Subcellular Location:
Secreted.

Post-translational modifications:
CXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes.

Similarity:
Belongs to the intercrine alpha (chemokine CxC) family.

SWISS:
P02778

Gene ID:
3627

Database links:

Entrez Gene: 3627 Human

Entrez Gene: 15945 Mouse

Entrez Gene: 245920 Rat

Omim: 147310 Human

SwissProt: P02778 Human

SwissProt: P17515 Mouse

SwissProt: P48973 Rat

Unigene: 632586 Human

Unigene: 877 Mouse

Unigene: 10584 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Human liver cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CXCL10) Polyclonal Antibody, Unconjugated (bs-23238R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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