| 產(chǎn)品編號(hào) | C07-01005 |
| 英文名稱(chēng) | Ac-YVAD-pNA |
| 中文名稱(chēng) | Caspase 1顯色底物 (Ac-YVAD-pNA) |
| 別 名 | N-α-acetyl-Tyr-Val-Ala-Asp-p-nitroanilide; Caspase Substrate, chromogenic; Caspase 1 substrate (chromogenic); Caspase-1 Substrate; N-Acetyl-Tyr-Val-Ala-Asp-p-Nitroanilide; Ac-YVAD-pNA (Caspase 1顯色底物) |
| CAS | 149231-66-3 |
| 保存條件 | Store at -20 °C for one year. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Ac-YVAD-pNA is a very selective chromogenic substrate for caspase-1, a key mediator of inflammatory processes formerly known as interleukin (IL)-1-converting enzyme. Ac-YVAD-pNA is used to determine caspase-1 activity. Cleavage of Ac-YVAD-pNA by caspase-1 releases pNA (p-nitroanilide), which can be quantified spectrophotometrically at 405 nm.
級(jí)別/純度：BR, ≥95% (HPLC) CSA：149231-66-3 分子式：C29H36N6O10 分子量：268.63 序列：N-Acetyl-Tyr-Val-Ala-Asp-p-Nitroanilide 來(lái)源：合成 溶解性：Soluble in DMSO 敏感性：對(duì)光敏感 簡(jiǎn)介：Ac-YVAD-pNA是Caspase 1的底物，被剪切后可產(chǎn)生黃色的pNA (p-nitroaniline)，pNA在405nm附近有強(qiáng)吸收，可以通過(guò)測(cè)定吸光度來(lái)檢測(cè)Caspase 1的活性。 用途：用作半胱氨酸的天冬氨酸蛋白水解酶顯色底物。 配方：5mg加入0.4ml DMSO，或每12.57mg加入1ml DMSO，配制成20mM溶液。20mM包裝用DMSO配制。 |
