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首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Mouse Anti-CCNA2  antibody (bsm-52043M)  
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說明書: 50ul  100ul  
50ul/1580.00元
100ul/2500.00元
大包裝/詢價
產(chǎn)品編號 bsm-52043M
英文名稱 Mouse Anti-CCNA2  antibody
中文名稱 周期素A2單克隆體
別    名 CCNA2_HUMAN; Cyclin-A2; Cyclin-A; CCN1; CCN1; CCNA; cyclin A2;   
Specific References  (1)     |     bsm-52043M has been referenced in 1 publications.
[IF=2.65] Ruoyang Lin. et al. Inhibitory Effects of Rabdosia rubescens in Esophageal Squamous Cell Carcinoma: Network Pharmacology and Experimental Validation. EVID-BASED COMPL ALT. 2022 Nov 10;2022:2696347  WB ;  Human.  
研究領(lǐng)域 腫瘤  心血管  細胞生物  細胞周期蛋白  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 2E9
交叉反應 (predicted: Human,Mouse,Rat)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:50-200,ICC/IF=1:50-200,IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 49kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human CCNA2 protein (1-150aa) 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle. This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M. [provided by RefSeq, Aug 2016]

Function:
Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.

Subunit:
Interacts with the CDK1 and CDK2 protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. When associated with CDK2 (but not with CDK1), interacts with SCAPER.

Subcellular Location:
Nucleus. Cytoplasm. Note=Cytoplasmic when associated with SCAPER.

Post-translational modifications:
Polyubiquitinated via 'Lys-11'-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase.

Similarity:
Belongs to the cyclin family. Cyclin AB subfamily.

SWISS:
P51943

Gene ID:
890

Database links:

Entrez Gene: 890 Human

Entrez Gene: 12428 Mouse

Entrez Gene: 114494 Rat

Omim: 123835 Human

SwissProt: P20248 Human

SwissProt: P51943 Mouse

Unigene: 58974 Human

Unigene: 4189 Mouse

Unigene: 13094 Rat



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