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Recombinant SARS-Cov-2 Spike RBD protein (N501Y), His (HEK293) (bs-46011P)  
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說明書: 下載
100ug/3980.00元
500ug/12500.00元
1mg/38000.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-46011P
英文名稱 Recombinant SARS-Cov-2 Spike RBD protein (N501Y), His (HEK293)
中文名稱 重組SARS冠狀病毒2 Spike突變蛋白R(shí)BD(N501Y) (His Tag)
別    名 SARS-CoV-2 spike protein; 2019-nCOV Spike protein; Spike glycoprotein; Spike protein S1; Surface glycoprotein; Spike protein RBD; SPIKE_SARS2; 2019-nCOV Spike protein(N501Y), Recombinant (His Tag); Recombinant SARS-COV-2 S protein RBD (N501Y) Protein. ;Recombinant SARS-Cov-2 Spike RBD protein (N501Y), His (HEK293)  突變型新冠蛋白; 新冠病毒S蛋白突變體(N501Y); 重組新冠病毒 Spike突變蛋白R(shí)BD(N501Y); 新型冠狀病毒Spike突變體蛋白;
理論分子量 26.2kDa
檢測(cè)分子量 35
性    狀 Lyophilized or Liquid
濃    度 >0.5 mg/ml
物    種 SARS-Cov-2
序    列 319-541/1273
純    度 >95% as determined by SDS-PAGE
純化方法 AC
內(nèi)毒素 Not analyzed
表達(dá)系統(tǒng) HEK293 cell
活性 Yes
標(biāo)簽 His
緩 沖 液 Lyophilized from 0.22um filtered solution in PBS (pH7.4). Normally 5% trehalose is added as protectant before lyophilization.
保存條件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein.

SWISS:
P0DTC2

Gene ID:
43740568

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