| 產(chǎn)品編號(hào) | bs-24881R |
| 英文名稱 | Rabbit Anti-Nkx2.5 antibody |
| 中文名稱 | 心臟特異性同源盒轉(zhuǎn)錄因子NKX2.5抗體 |
| 別 名 | Cardiac-specific homeobox 1; Cardiac-specific homeobox 1; Cardiac-specific homeobox; CHNG5; CSX; CSX1; Homeobox protein CSX; Homeobox protein NK-2 homolog E; NK2 transcription factor related, locus 5 (Drosophila); Nkx2-5; NKX2.5; Nkx2E; NKX4-1; Tinman paralog. |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 干細(xì)胞 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 36kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse Nkx2.5 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
In humans, mutations of the gene encoding the homeobox transcription factor Nkx2.5 result in electrical conduction defects and morphological abnormalities of the heart (Dupays et al., 2005). In the heart, Nkx2.5 is expressed in both the myocardium and the endocardium. Differentiation of embryonic stem cells to Nkx2.5-positive cardiomyocytes is facilitated by Wnt11. Subcellular Location: Nuclear SWISS: P42582 Gene ID: 18091 Database links: Clone ID: 396073 Chicken Entrez Gene: 1482 Human Entrez Gene: 18091 Mouse Omim: 600584 Human SwissProt: Q90788 Chicken SwissProt: P52952 Human SwissProt: P42582 Mouse Unigene: 638 Chicken Unigene: 54473 Human Unigene: 41974 Mouse Unigene: 6179 Rat |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Heart tissue lysates
Lane 2: Rat Heart tissue lysates
Primary: Anti-Nkx2.5 (bs-24881R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 36 kD
Observed band size: 42 kD
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