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Rabbit Anti-RHOJ  antibody (bs-25181R)  
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產(chǎn)品編號 bs-25181R
英文名稱 Rabbit Anti-RHOJ  antibody
中文名稱 RHOJ蛋白抗體
別    名 ARHJ; FLJ14445; MGC34777; Ras homolog family member J; Ras homolog gene family member J; RAS like family 7 member B; Ras like protein family member 7B; Ras-like protein family member 7B; RASL 7B; RASL7B; Rho related GTP binding protein RhoJ; Rho-related GTP-binding protein RhoJ; RHOI; Rhoj; RHOJ_HUMAN; Tc10 like GTP binding protein TCL; TC10 like Rho GTPase; Tc10-like GTP-binding protein; TC10B; TCL.  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導(dǎo)  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat (predicted: Human,Mouse,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:400-800,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 24kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RHOJ: 61-160/214 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis. [provided by RefSeq, Dec 2011]

Function:
GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology.

Subunit:
Interacts with the CRIB domains of proteins such as Pak1 and Was/Wasp.

Subcellular Location:
Cell membrane.

Similarity:
Belongs to the small GTPase superfamily. Rho family.

SWISS:
Q9H4E5

Gene ID:
57381

Database links:

Entrez Gene: 57381 Human

Entrez Gene: 80837 Mouse

Entrez Gene: 299145 Rat

Omim: 607653 Human

SwissProt: Q9H4E5 Human

SwissProt: Q9ER71 Mouse

Unigene: 656339 Human

Unigene: 27467 Mouse

Unigene: 228606 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (RHOJ) Polyclonal Antibody, Unconjugated (bs-25181R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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