| 產(chǎn)品編號(hào) | bs-25205R |
| 英文名稱(chēng) | Rabbit Anti-RNASE4 antibody |
| 中文名稱(chēng) | 核糖核酸酶4抗體 |
| 別 名 | RAB1; Ribonuclease 4; Ribonuclease A B1; Ribonuclease, RNase A family, 4; RNAS4_HUMAN; RNase 4; RNS4. |
| 研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 血管內(nèi)皮細(xì)胞 細(xì)胞骨架 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Rat (predicted: Mouse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:400-800,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 14kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse RNASE4: 91-190/148 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene belongs to the pancreatic ribonuclease family. It plays an important role in mRNA cleavage and has marked specificity towards the 3' side of uridine nucleotides. Alternative splicing results in four transcript variants encoding the same protein. This gene and the gene that encodes angiogenin share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2013]. Function: This RNase has marked specificity towards the 3' side of uridine nucleotides. Subcellular Location: Secreted. Similarity: Belongs to the pancreatic ribonuclease family. SWISS: Q9JJH1 Gene ID: 58809 Database links: Entrez Gene: 465205 Chimpanzee Entrez Gene: 6038 Human Entrez Gene: 58809 Mouse Entrez Gene: 100174757 Orangutan Omim: 601030 Human SwissProt: Q8HZQ0 Chimpanzee SwissProt: P34096 Human SwissProt: Q9JJH1 Mouse SwissProt: Q5NVS4 Orangutan Unigene: 730830 Human Unigene: 202665 Mouse Unigene: 1742 Rat |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (RNASE4) Polyclonal Antibody, Unconjugated (bs-25205R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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