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Mouse Anti-THEM2  antibody (bsm-34228M)  
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產(chǎn)品編號 bsm-34228M
英文名稱 Mouse Anti-THEM2  antibody
中文名稱 ?;o酶A硫酯酶13單克隆抗體
別    名 15 Kd protein ; ACO13_HUMAN ; Acot13 ; Acyl-CoA thioesterase 13 ; Acyl-coenzyme A thioesterase 13 ; HT012 ; hypothalamus protein HT012 ; MGC4961 ; PNAS 27 ; PNAS27 ; Thioesterase superfamily member 2   
研究領(lǐng)域 信號轉(zhuǎn)導(dǎo)  細(xì)胞骨架  細(xì)胞外基質(zhì)  
抗體來源 Mouse
克隆類型 Monoclonal
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 15kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human THEM2 protein 
亞    型 IgG1,k
純化方法 affinity purified by Protein A
緩 沖 液 PBS with 0.02% Proclin300.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2009]

Function:
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16934754, PubMed:19170545). Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates (By similarity) (PubMed:16934754, PubMed:19170545). Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro) (By similarity) (PubMed:16934754, PubMed:19170545). May play a role in controlling adaptive thermogenesis (By similarity).

Similarity:
Belongs to the thioesterase PaaI family.

SWISS:
Q9NPJ3

Gene ID:
55856

產(chǎn)品圖片
All lanes : Anti-THEM2 Antibodyat 1:1000 dilution Lane 1: HepG2 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 15 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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