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Mouse Anti-SERPINB3  antibody (bsm-43190M)  
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產(chǎn)品編號 bsm-43190M
英文名稱 Mouse Anti-SERPINB3  antibody
中文名稱 絲氨酸蛋白酶抑制劑B3單克隆抗體
別    名 HsT1196; Protein T4 A; Protein T4-A; SCC; SCCA PD; SCCA-1; SCCA1; SCCAPD; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 3; Serpin B3; Serpin peptidase inhibitor clade B (ovalbumin) member 3; SERPINB3; SPB3_HUMAN; Squamous cell carcinoma antigen 1; T4 A; T4A.  
抗體來源 Mouse
克隆類型 Monoclonal
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 46kDa
細(xì)胞定位 細(xì)胞漿 分泌型蛋白 
性    狀 Liquid
免 疫 原 Recombinant human SERPINB3 protein 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹

Enables cysteine-type endopeptidase inhibitor activity; protease binding activity; and virus receptor activity. Involved in several processes, including autocrine signaling; paracrine signaling; and regulation of cellular protein metabolic process. Located in cytoplasmic vesicle; extracellular exosome; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]




Function:
May act as a protease inhibitor to modulate the host immune response against tumor cells.

Subcellular Location:
Cytoplasm. Seems to also be secreted in plasma by cancerous cells but at a low level.

Tissue Specificity:
Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).

Similarity:
Belongs to the serpin family. Ov-serpin subfamily.

SWISS:
P29508

Gene ID:
6317

Database links:

Entrez Gene : 6317 Human

Omim : 600517 Human

SwissProt : P29508 Human

Unigene : 227948 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded Human Esophagus; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(bsm-43190M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Prostate; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(bsm-43190M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Cervical Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(bsm-43190M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Lung squamous cell carcinoma; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(bsm-43190M) at 1:200 overnight at 4°C, followed by conjugation to the bs-40296G-HRP and DAB (C-0010) staining.
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